Mr. Myles Smith and his colleagues in the Sarcoma and Melanoma Unit at the Royal Marsden, recently published a study in the European Journal of Surgical Oncology. The study was titled, Low Local Recurrence Rates Following Marginal Surgical Resection of Non-Coelomic Atypical Lipomatous Tumours/Well-Differentiated Liposarcomas.
Atypical Lipomatous tumours or well-differentiated liposarcomas (ALT/WDLS) are low-grade soft tissue sarcomas, and make up about 50% of all liposarcoma diagnoses. They are a slow-growing painless tumour, commonly found in the extremities, especially the thigh, or in the abdomen. They do not usually spread to other parts of the body, but they have a tendency to regrow after initial treatment, commonly after a surgical marginal resection.
The aim of this study was to identify patients who underwent surgery for confirmed preoperative diagnosis (MRI and core needle biopsy) of non-coelomic ALT, to ascertain the local recurrence rate and those who may be at low risk for local relapse. It looked at the results from 127 patients, split evenly male and female, with an average age of 61 over a 16-year period. 85% of the cases were in a lower limb.
The study found that function-preserving marginal resection of non-coelomic ALTs has low local recurrence and extremely low rates of distant relapse. Patients who underwent marginal resection in the lower limb had the lowest rate of distant relapse, with all recurrences in the thigh. There was also a low morbidity rate.
For more advice, call us on 020 3770 5864 to arrange an appointment at the HCA Lister Hospital Clinics (Chelsea Outpatient Centre and Chiswick Medical Centre) or call 020 7808 2785 to book a consultation with Mr Myles Smith at the Royal Marsden Hospital.